Effectiveness: With Lamotrigine, The proportion of patients with syndromal depression decreased significantly. The proportions with euthymia and subsyndromal depression increased significantly. Lamotrigine primarily maintained euthymia in 55 trials initiated prior to Stanford during mean 530 days.
Abstract
Lamotrigine, Top: 2 pi charts shown, showing the % of people with euthymia/ depression at baseline and after 395 days. Bottom: 2 pi charts, showing % of people with depression and euthymia in the study sample at baseline and after 530 days.